Ethanol toxicity is also associated with respiratory depression which results into respiratory arrest, hypothermia, cardiac dysrhythmias with possible cardiac arrest, hypoglycemia, ketoacidosis and hypotension ( Gormley et al., 2012).Ĭurrent review was designed with main objective to highlight the toxic and serious health risks to human health and environment by frequent using hand hygiene products with alcohols based formulations. Toxicological reviews of methanol published by public health England showed oral and dermal toxicity of methanol with observation not to use in hand hygiene products ( Public Health England, 2015). Ingestion of isopropyl alcohol accidentally or deliberately leads to severe respiratory or central nervous system depression ( Slaughter et al., 2014). It is recognized that ingestion of low concentration of hydrogen peroxide (3% solution) is responsible for minor gastrointestinal tract irritation ( Moon et al., 2006) and in few cases it is also responsible for portal vein embolism ( Sung et al., 2018) and mild mucosal irritating and vomiting ( ATSDR, 2014). These chemicals have known toxic and hazardous impact on environment when released by evaporation ( Slaughter et al., 2014). These preparations may become toxic to human health and environment when misused. WHO recommended alcohol based hand sanitizers are mainly made up from ethanol, isopropyl alcohols, hydrogen peroxides in different combinations ( WHO, 2020). These recommendations are based on fast, effective and broad spectrum anti-microbial activity combined with easy availability and considered safety. WHO suggested two alcohols based formulations for hands hygiene in healthcare to sensitize the hands and to reduce the spread and infectivity of coronavirus ( WHO, 2020). Adaptation of effective hand hygiene is vital, where one of the best advices by WHO is to wash or sanitize your hands frequently with soap or >60% alcoholic hand sanitizer, respectively. In current scenario preventive measures and healthy life style with efficient immune system have been suggested by WHO to fight and stay safe from COVID-19. So far, no medication or vaccine is available to cope with this novel coronavirus and infection rate is increasing drastically across the globe. Humans are main transmission source of SARS-CoV-2 through human to human interactions in case, any infected person with mild or even no symptoms come in contact with healthy person ( Kratzel et al., 2020). COVID-19 has been declared as pandemic by World Health Organization (WHO) in Maand till Jconfirmed infections are 9,110,186 with 473,061 deaths across 216 countries ( WHO, 2020). This disease is characterized by acute respiratory disorder, pneumonia, dry cough, fever and body pain with high rate of mortality, particularly in older people or those with underlying health conditions ( Lai et al., 2020). Current review is designed with main objective to highlight the toxic and serious health risks to human health and environment by frequent using hand hygiene products with alcohols based formulations.ĬOVID-19 (Coronavirus disease-2019), the novel and new disease spreads through recent coronavirus 2 (SARS-CoV-2) from Wuhan, China ( Huang et al., 2020). Furthermore, frequent usage of said hand sanitizers has reported increased chance of antimicrobial resistance and chance of other viral diseases. In early five months of 2020, American Association of Poison Control Center reported 9504 alcoholic hand sanitizer exposure cases in children under the age of 12 years and recognized that even a small amount of alcohol can cause alcohol poisoning in children that is responsible for confusion, vomiting and drowsiness, and in severe cases, respiratory arrest and death. These chemicals have known toxic and hazardous impact on environment when released by evaporation. ![]() WHO recommended alcohol based hand sanitizers for frequent hand hygiene, which are mainly made up from ethanol, isopropyl alcohols, hydrogen peroxides in different combinations. Only preventive measures and healthy life style with efficient immune system have been suggested by WHO to fight and stay safe from COVID-19. ![]() Till date no medication or vaccine is available to cope with the COVID-19 infection and infection rate is increasing drastically across the globe.
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